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First Evidence-Based Guidelines for Pediatric Patients with Sepsis Issued

The international Surviving Sepsis Campaign has issued the first evidence-based guidelines targeted for pediatric sepsis. Sepsis affects more than 75,000 children per year in the United States and results in significant morbidity and mortality. Recognizing which children require sepsis treatment remains a key challenge.

While the adult sepsis guidelines recommend that all patients with sepsis begin antimicrobial therapy within one hour of diagnosis, Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children recommends a two-phase process for assessing children with suspected sepsis.

HAP recognized that early recognition of sepsis in pediatric patients is a gap in current sepsis care. HAP collaborated with The Children’s Hospital of Philadelphia to launch a pilot program during 2018 to better recognize sepsis in pediatric patients in emergency rooms to further improve sepsis outcomes in children. The pilot concluded that implementation of an electronic alert with bedside assessment is feasible in community emergency departments and may improve the emergent care of children with presumed sepsis.

HAP’s pediatric sepsis pilot complements a comprehensive array of quality improvement work targeting severe sepsis and septic shock and sepsis readmissions through HAP’s Hospital Improvement Innovation Network (HIIN). HAP also will provide additional insights and best practices in sepsis prevention and treatment during its 2020 HAP Patient Safety, Quality, and Sepsis Symposium, September 9–10, in Lancaster.

For more information about HAP’s sepsis work, contact Maggie Miller, HAP’s sepsis project manager.

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